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Propylene Glycol

  • Propylene Glycol
  • Propylene Glycol
  • Propylene Glycol

Propylene Glycol

Propylene Glycol
CAS No.: 57-55-6
Molecular Formula: C3H8O2
Molecular Weight: 76.09

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PRODUCT DESCRIPTION

Propylene Glycol USP/EP/FCC (CAS 57-55-6) is a high-purity (>99.5%) multi-functional liquid solvent and humectant compliant with global pharmacopeia standards. As a USP-grade pharmaceutical excipient, it serves as low-endotoxin (≤0.5EU/ml) injection solvent; in cosmetics, it acts as OECD 439-certified low-irritant humectant; for food processing, FCC-grade PG functions as antifreeze carrier (21 CFR 184.1666); while industrial applications leverage its low-toxicity antifreeze properties (-59°C, ASTM D1384). Technical documentation available.


Chemical Properties

PropertyValue
Melting point-60 °C (lit.)
Boiling point187 °C (lit.)
Density1.036 g/mL at 25 °C (lit.)
Vapor density2.62 (vs air)
Vapor pressure0.08 mm Hg ( 20 °C)
Refractive indexn20/D1.432(lit.)
FEMA2940 | PROPYLENE GLYCOL
Fp225 °F
Storage temp.Store at +5°C to +30°C.
SolubilityChloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Pka14.49±0.20(Predicted)
FormViscous Liquid
ColorAPHA: ≤10
Specific Gravity1.038 (20/20℃)1.036～1.040
PH6-8 (100g/l, H2O, 20℃)
Odorat 100.00 %. odorless very slight alcoholic
Odor Typeodorless
Optical Rotation-0.11° (C=1.00g/100ml, CHCL3)
biological sourcesynthetic
explosive limit2.4-17.4%(V)
Water Solubilitymiscible
SensitiveHygroscopic
Merck14,7855
JECFA Number925
BRN1340498
Dielectric constant32.0
InChIKeyDNIAPMSPPWPWGF-UHFFFAOYSA-N
LogP-0.92
Surface tension35.44mN/m at 298.15K
CAS DataBase Reference57-55-6(CAS DataBase Reference)
NIST Chemistry ReferencePropylene glycol(57-55-6)
EPA Substance Registry SystemPropylene glycol (57-55-6)


Safety Information

PropertyValue
Safety Statements24/25
WGK Germany1
RTECSTY2000000
Autoignition Temperature779 °F
TSCAYes
HS Code29053200
Hazardous Substances Data57-55-6(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 19400 - 36000 mg/kg LD50 dermal Rabbit 20800 mg/kg


Product Usage

Propylene glycol is a versatile, colorless, and odorless liquid widely utilized for its excellent solvent, humectant, and preservative properties. In the food and beverage industry, it serves as a safe carrier for flavors and colors, and as a humectant to maintain moisture in baked goods and dairy products. Its role in cosmetics and personal care is equally vital, acting as a moisture-retaining agent in lotions, shampoos, and toothpastes to ensure smooth application and skin hydration. In the pharmaceutical sector, it is used as a solvent for injectable and oral medications to enhance stability and absorption. Additionally, it has significant industrial applications, notably as a non-toxic antifreeze and heat-transfer fluid in HVAC systems, as well as a key raw material for manufacturing high-performance unsaturated polyester resins.

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